NIAID Resources

The National Institute of Allergy and Infectious Diseases (NIAID), one of the National Institutes of Health (NIH), is dedicated to conducting and supporting research to better understand, treat, and prevent infectious diseases, such as influenza. NIAID has invested in infectious disease research programs, data repositories, and resources; links to each are provided below. 

Research Programs

The NIH and NIAID have established programs that bring investigators together and support collaborative immunology and influenza research. 

  • HIPC

    The Human Immunology Project Consortium (HIPC) program uses computational methods and analytic tools with human cohort studies to generate accessible data and a comprehensive understanding of the human immune system.

  • CEIRR

    The Centers of Excellence for Influenza Research and Response (CEIRR) program conducts studies both in the United States and internationally to better understand influenza and other diseases and supports pandemic emergency research responses.

  • CEIRS

    The Centers of Excellence for Influenza Research and Surveillance (CEIRS) was a NIAID supported program from 2014 - 2021. The overall goal of the CEIRS Network was to perform research, provide data, and create public health tools needed to control the impact of epidemic influenza and the threat of pandemic influenza.

  • Influenza Page

    NIAID's influenza page is central resource for influenza programs and provides information on the science conducted by NIAID-funded laboratories.

Data Repositories

The NIH and NIAID both support and fund various data sharing repositories. These data repositories store, organize, validate, archive, preserve, and distribute submissions of relevant data from the community. 

  • BV-BRC

    The Bacterial and Viral Bioinformatics Resource Center (BV-BRC) is an information system for biomedical researchers supporting resources for microbial genome sequences, host data on protein structure and function, clinical studies, drug targets and resistance, and epidemiology. BV-BRC has open-source tools for data analysis and genomic annotation.

  • IEDB

    The Immune Epitope Database (IEDB) catalogs experimental data on antibody and T cell epitopes in human, non-human primates and other animals, and supports prediction and analysis of epitopes.

  • ImmPort

    The Immunology Database and Analysis Portal (ImmPort) supports data deposition from NIH-funded programs, other research organizations and individual scientists to share and support clinical and basic research data.

  • IRD

    The Influenza Research Database (IRD) supports avian and non-human mammalian influenza surveillance data, human clinical data associated with virus extracts, phenotypic characteristics of viruses isolated from extracts, and all genomic and proteomic data available in public repositories for influenza viruses.

Resources

The following sites provide investigators central resources to support the conduct and management of research.  

  • BEI

    The Biodefense and Emerging Infections Research Resources Repository (BEI) is a repository to supply organisms and reagents for basic researchers in the development of improved diagnostics, vaccines, and therapies.

  • CROMS

    The Clinical Research Operations and Management Support (CROMS) platform provides centralized data management to support clinical research for both NIAID and extramural investigators.

  • TCF

    The NIH Tetramer Core Facility (TCF) provides researchers with major histocompatibility complex (MHC) tetramers and related reagents for the detection of T cell responses to viruses and other model antigens.

  • VAC

    The Vaccine Adjuvant Compendium (VAC) compiles metadata on novel adjuvant research and characteristic studies to help vaccine developers identify suitable adjuvants for various vaccine indications, including immune-mediated and infectious diseases.